Background:This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1.
仕様
Synonyms:Charged multivesicular body protein 4b,CHM4B,chmp4b,Chromatin-modifying protein 4b,hSnf7-2,hVps32-2,SNF7 homolog associated with Alix 1,SNF7-2,Vacuolar protein sorting-associated protein 32-2,Vps32-2
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human CHMP4B
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:Q9H444
Isotype:IgG
Research Areas:Cancer, Cell Biology, Microbiology, Signal transduction