Background:CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression. Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.
仕様
Synonyms:CENP P,CENP-P,cenpp,CENPP,Centromere protein P,FLJ33928,RP11-19J3.3
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human CENPP
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000
Swissprot:Q6IPU0
Isotype:IgG
Research Areas:Cell Biology, Epigenetics and Nuclear Signaling