Background:Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C.
仕様
Synonyms:CENP H,CENP-H,CENPH,CENPH,Centromere protein H,ICEN35,Interphase centromere complex protein 35,Kinetochore protein CENP H,NNF1,NNF1,MIND kinetochore complex component,homolog,PMF1
Host:Rabbit
Reactivity:Human
Applications:WB,ELISA
Concentration:0.2mg/mL
Immunogen:Recombinant protein of human CENPH
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:Q9H3R5
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling