Background:This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
仕様
Synonyms:Calnexin,CALX,CANX,CNX,FLJ26570,Histocompatibility complex class I antigen binding protein p88,IP90,Major histocompatibility complex class I antigen-binding protein p88,p90
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.7mg/mL
Immunogen:Recombinant protein of human CANX
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:50-1:200
Swissprot:P27824
Isotype:IgG
Research Areas:Cancer, Neuroscience, Tags & Cell Markers