Background：The protein encoded by this gene is an endogenous calpain （calcium-dependent cysteine protease） inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains （domains 1-4）, and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
仕様
Synonyms：BS 17,Calpain inhibitor,Calpastatin,Cast,Heart type calpastatin,ICAL,MGC9402,Sperm BS 17 component,Sperm BS-17 component
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.7mg/mL
Immunogen：Recombinant protein of human CAST
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
