Background：This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein （tau-crystallin） in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.
仕様
Synonyms：2 phospho D glycerate hydro lyase,2-phospho-D-glycerate hydro-lyase,Alpha enolase,Alpha enolase like 1,Alpha-enolase,C myc promoter binding protein,C-myc promoter-binding protein,EC 4.2.1.11,eno1,ENO1L1,ENOA,Enolase 1 （alpha）,Enolase 1 （alpha） like 1,Enolase 1,Enolase alpha,MBP 1,MBP-1,MBP1,MBPB1,MPB 1,MPB-1,MPB1,MYC promoter binding protein 1,NNE,Non neural enolase,Non-neural enolase,Phosphopyruvate hydratase,Plasminogen binding protein,Plasminogen-binding protein,PPH,Tau crystallin
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human ENO1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：P06733
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction
