Background：This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection.
仕様
Synonyms：4E-BP2,4EBP2,4EBP2,eIF4E binding protein 2,eIF4E-binding protein 2,Eif4ebp2,Eukaryotic translation initiation factor 4E binding protein 1,Eukaryotic translation initiation factor 4E-binding protein 2,PHASII,phosphorylated,heat and acid stable regulated by insulin protein II
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Recombinant protein of human EIF4EBP2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q13542
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Metabolism
