86-4097-47 ［取扱停止］Rabbit anti-BCAS2 Polyclonal Antibody 20uL RD77885A
[Reddot Biotech] Rabbit anti-BCAS2 Polyclonal Antibody 20uL
特徴
- Background：BCAS2 （breast carcinoma amplified sequence 2）, also designated DAM1 （DNA amplified in mammary carcinoma 1 protein） or spliceosome-associated SPF 27, is a ubiquitously expressed nuclear protein that was originally identified as being overexpressed in various breast cancer cell lines. BCAS2 is now known to be a component of the spliceosome, participating in the removal of introns from mRNA precursors. BCAS2 specifically interacts （in a ligand-independent manner） with TR∫ （thyroid hormone receptor beta）, ERa （estrogen receptor alpha）, ER∫, PR （progesterone receptor）, and PPAR© （Peroxisome proliferator-activated receptor gamma）. BCAS2 functions as an ER coactivator and is capable of enhancing ER-mediated transcription. This suggests that BCAS2 is involved in the development of breast cancer.
仕様
- Synonyms：bcas2,Breast carcinoma amplified sequence 2,Breast carcinoma-amplified sequence 2,DAM1,DNA amplified in mammary carcinoma 1 protein,MGC7712,Pre mRNA splicing factor SPF27,Pre-mRNA-splicing factor spf27,Snt309,SPF27,SPF27,Spliceosome associated protein amplified in breast cancer,Spliceosome associated protein SPF 27,Spliceosome-associated protein SPF 27
- Host：Rabbit
- Reactivity：Human,Mouse
- Applications：WB,IHC,ELISA
- Concentration：0.5mg/mL
- Immunogen：Recombinant protein of human BCAS2
- Purification Method：Affinity purification
- Clonality：Polyclonal
- Conjugation：Unconjugated
- Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
- Dilution：WB 1：200-1：1000, IHC 1：50-1：200
- Swissprot：O75934
- Isotype：IgG
- Research Areas：Cancer, Epigenetics and Nuclear Signaling, Tags ＆ Cell Markers
- サイズ：20uL
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