Background：This gene encodes a member of the ankyrin repeat and SOCS box-containing （ASB） protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signaling （SOCS） proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仕様
Synonyms：Ankyrin repeat and SOCS box 2 containing protein,Ankyrin repeat and SOCS box containing 2,Ankyrin repeat and SOCS box containing protein 2,Ankyrin repeat and SOCS box containing protein 2a,Ankyrin repeat and SOCS box protein 2,Ankyrin repeat containing protein ASB2,ASB 2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Recombinant protein of human ASB2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q96Q27
Isotype：IgG
Research Areas：Cell Biology, Epigenetics and Nuclear Signaling
