Background：Activating signal co-integrator-1 （ASC-1）, originally identified as TRIP4, is a transcriptional co-activator of nuclear receptors that associates with specific components of the RNA polymerase II complex and binds the basal transcription factors TBP and TFIIA. ASC-1 functions with the transcription integrators SRC-1 and CBP/p300 through its zinc finger motif and is dependent on their ligand-dependent transactivation domain, AF2. Endogenous ASC-1 in HeLa cells is predominantly a nuclear protein. Under conditions of serum starvation, ASC-1 localizes to the cytoplasm.
仕様
Synonyms：Activating signal cointegrator 1,ASC 1,ASC-1,HsT17391,Thyroid hormone receptor interactor 4,Thyroid receptor interacting protein 4,Thyroid receptor-interacting protein 4,TR-interacting protein 4,TRIP 4,TRIP-4,Trip4,TRIP4,ZC2HC5,Zinc finger C2HC5 type
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Recombinant protein of human TRIP4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
