Background：The full-lengthSTK17BcDNA clone encodes a deduced 372-amino acid protein with a molecular mass of 42.34 kD. The putative kinase domain is located at the N terminus and contains all 11 subdomains conserved among ser/thr kinases. STK17A andSTK17Bshare 59.7％ amino acid identity.Northern blot analysis revealed that STK17B was expressed in various tissues, such as heart, placenta, liver, and pancreas, as different-sized transcripts, presumably due to differences in the 3-prime untranslated region. Transient transfection of COS-7 cells showed that STK17B localized in nuclei. Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis.
仕様
Synonyms：DAP kinase related apoptosis inducing protein,DAP kinase related apoptosis inducing protein kinase 2,DAP kinase-related apoptosis-inducing protein kinase 2,Death associated protein kinase related 2,DRAK 2,DRAK2,Serine/threonine kinase 17b,Serine/threonine kinase 17b apoptosis inducing,Serine/threonine protein kinase 17B,Serine/threonine-protein kinase 17B,ST17B,STK 17B,Stk17b
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Recombinant protein of human STK17B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：O94768
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
