Background：Krueppel-like factor 17is aproteinthat in humans is encoded by theKLF17gene. Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
仕様
Synonyms：FLJ40160,KLF17,KLF17,Krueppel like factor 17,Krueppel-like factor 17,Novel zinc finger protein,RP4 675G8.1,RP4675G8.1,Zfp393,Zinc finger protein 393,ZNF393
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human KLF17
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
