Background：The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：59 kDa,A 116A10.1,Amyloid beta precursor protein binding protein 1 59kD,Amyloid beta precursor protein binding protein 1 59kDa,Amyloid beta precursor protein binding protein 1,Amyloid beta precursor protein binding protein 1,59 kDa,Amyloid beta precursor protein-binding protein 1,Amyloid protein binding protein 1,Amyloid protein-binding protein 1,APP BP1,APP-BP1,APPBP 1,APPBP1,HPP 1,HPP1,NAE 1,NAE1,NEDD8 activating enzyme E1 regulatory subunit,NEDD8 activating enzyme E1 subunit 1,NEDD8 activating enzyme E1 subunit,NEDD8-activating enzyme E1 regulatory subunit,Proto oncogene protein 1,Proto-oncogene protein 1,Protooncogene protein 1,ula 1,ULA1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.1mg/mL
Immunogen：Recombinant protein of human NAE1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：Q13564
Isotype：IgG
Research Areas：Cell Biology, Epigenetics and Nuclear Signaling
