Background:Autophagy protein 5is aproteinthat in humans is encoded by theATG5gene.It is an E3ubiquitinligasewhich is necessary forautophagydue to its role inautophagosomeelongation. It is activated byATG7and forms a complex withATG12andATG16L1. This complex is necessary for LC3-1 conjugation toPEto form LC3-II.
仕様
Synonyms:APG 5,APG 5L,APG5,APG5 autophagy 5 like,APG5 like,APG5-like,APG5L,Apoptosis specific protein,Apoptosis-specific protein,ASP,ATG 5,Atg5,ATG5 autophagy related 5 homolog,ATG5,Autophagy protein 5,Autophagy related 5,hAPG5,Homolog of S Cerevisiae autophagy 5,OTTHUMP00000040507
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.5mg/mL
Immunogen:Recombinant protein of human ATG5
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:Q9H1Y0
Isotype:IgG
Research Areas:Cancer, Cell Biology, Cardiovascular, Metabolism, Signal transduction