Background:The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
仕様
Synonyms:SERPINA3,AACT,AACT,ACT,Alpha-1-antichymotrypsin His-Pro-less,Antichymotrypsin,Cell growth inhibiting gene 24/25 protein,Cell growth-inhibiting gene 24/25 protein,GIG24,GIG25,Growth inhibiting protein 24,Growth inhibiting protein 25,MGC88254,Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase,antitrypsin) member 3,Serine (or cysteine) proteinase inhibitor clade A member 3,Serine proteinase inhibitor clade A member 3,Serpin A3,Serpin family A member 3,Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3,SERPINA3
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human SERPINA3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:P01011
Isotype:IgG
Research Areas:Cancer, Cell Biology, Cardiovascular, Neuroscience