Background：This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
仕様
Synonyms：1110038I05Rik,AI314632,Aldehyde dehydrogenase 6 family member A1,Aldehyde dehydrogenase family 6 member A1,Aldehyde dehydrogenase family 6,subfamily A1,ALDH6A1,Malonate semialdehyde dehydrogenase,Malonate-semialdehyde dehydrogenase [acylating],Methylmalonate semialdehyde dehydrogenase [acylating] mitochondrial,Methylmalonate-semialdehyde dehydrogenase [acylating],MGC37325,MGC40271,Mitochondrial acylating methylmalonate semialdehyde dehydrogenase,mitochondrial,MMSA,MMSADHA,MMSDH
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human ALDH6A1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：50-1：200
Swissprot：Q02252
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
