Background:This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.
仕様
Synonyms:AC4,Adcy4,ADCY4,Adenylate cyclase 4,Adenylate cyclase type 4,Adenylate cyclase type IV,Adenylyl cyclase 4,Adenylyl cyclase,ATP pyrophosphate lyase 4,ATP pyrophosphate lyase,ATP pyrophosphate-lyase 4
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human ADCY4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:Q8NFM4
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction