Background：This gene encodes a member of the ADAMTS （a disintegrin and metalloproteinase with thrombospondin motifs） protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 （TS） motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
仕様
Synonyms：A disintegrin and metalloproteinase with thrombospondin motifs 18,A disintegrin like and metalloprotease （reprolysin type） with thrombospondin type 1 motif 18,A disintegrin like and metalloprotease （reprolysin type） with thrombospondin type 1 motif 21,ADAM metallopeptidase with thrombospondin type 1 motif 18,ADAM-TS 18,ADAM-TS18,ADAMTS 18,ADAMTS-18,ADAMTS18,ADAMTS21,ATS18,Disintegrin and metalloprotease like protein,EC 3.4.24.,KNO2
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.2mg/mL
Immunogen：Recombinant protein of human ADAMTS18
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q8TE60
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
