Background：This gene encodes a member of the ADAMTS （a disintegrin and metalloproteinase with thrombospondin motifs） and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 （TS） motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia.
仕様
Synonyms：ADAMTS like 2,ADAMTS like protein 2,ADAMTS-like protein 2,ADAMTSL 2,ADAMTSL-2,ADAMTSL2,ATL2,FLJ45164,KIAA0605
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.1mg/mL
Immunogen：Recombinant protein of human ADAMTSL2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：Q86TH1
Isotype：IgG
Research Areas：Developmental biology, Signal transduction
