Background：This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol （2-AG）, the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC （polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract）, resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
仕様
Synonyms：2-arachidonoylglycerol hydrolase,6330583M11Rik,ABD12,ABHD12,ABHD12A,Abhydrolase domain containing protein 12,Abhydrolase domain-containing protein 12,AI431047,AW547313,BEM46L2,C20orf22,Monoacylglycerol lipase ABHD12,RP23-241M12.2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.2mg/mL
Immunogen：Recombinant protein of human ABHD12
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
