Background：The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine （in vitro）. Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.
仕様
Synonyms：2OG Fe（II） oxy DC1,9530023G02,ABH 2,ABH2,alkB alkylation repair homolog 2,ALKB2,ALKBH2 alkB,ALKBH2,Alkylated DNA repair protein alkB homolog,Alkylated DNA repair protein alkB homolog 2,Alkylation repair homolog 2,Alpha ketoglutarate dependent dioxygenase alkB homolog 2,Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2,AU016977,DNA oxidative demethylase ALKBH2,EC 1.14.11.,FLJ99103,hABH2,mABH2,MGC90512,Oxy DC1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human ALKBH2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
