Background：The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette （ABC） transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies （ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White）. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
仕様
Synonyms：ABC,ABC transporter umat,ABC14,Abcb6,ABCB6,ATP binding cassette sub family B member 6,mitochondrial precursor,ATP binding cassette,sub family B （MDR/TAP）,member 6,ATP-binding cassette half-transporter,ATP-binding cassette sub-family B member 6,ATP-binding cassette sub-family B member 6,mitochondrial,DUH3,LAN,MCOPCB7,Mitochondrial ABC transporter 3,mitochondrial,Mt ABC transporter 3,Mt-ABC transporter 3,MTABC3,P glycoprotein related protein,P-glycoprotein-related protein,PRP,Ubiquitously expressed mammalian ABC half transporter,Ubiquitously-expressed mammalian ABC half transporter,UMAT
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.1mg/mL
Immunogen：Recombinant protein of human ABCB6
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：Q9NP58
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
