Background：The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor （CIS）, also known as suppressor of cytokine signaling （SOCS） or STAT-induced STAT inhibitor （SSI）, protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia （CML） and erythroleukemia （HEL） cell lines.
仕様
Synonyms：CIS-4,CIS4,Cish4,Cytokine inducible SH2 protein 4,Cytokine-inducible SH2 protein 4,HSPC060,SOCS-4,SOCS-6,SOCS4,Socs6,SOCS6,SSI4,STAI4,STAT induced STAT inhibitor 4,STAT4,STATI4,Suppressor of cytokine signaling 4,Suppressor of cytokine signaling 6
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human SOCS6
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：O14544
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Signal transduction
