Background:Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
仕様
Synonyms:bA416N4.2,Bdr,CMS18,dJ1068F16.2,FLJ23079,HGNC:11132,MGC105414,MGC139754,Resistance to inhibitors of cholinesterase 4 homolog,RIC 4,RIC4,SEC 9,SEC9,SNAP 25,SNAP,SNAP-25,SNAP-25B,SNAP25,SNP 25,SNP25,SNP25,sp,SUP,Super protein,Synaptosomal associated 25 kDa protein,Synaptosomal associated protein,Synaptosomal associated protein 25,Synaptosomal associated protein 25kDa,Synaptosomal-associated 25 kDa protein,Synaptosomal-associated protein 25,Synaptosomal-associated protein,25-KD
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.2mg/mL
Immunogen:Recombinant protein of human SNAP25
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000
Swissprot:P60880
Isotype:IgG
Research Areas:Cancer, Metabolism, Neuroscience, Signal transduction