Background：This gene encodes a member of the SLC12A transporter family. The encoded protein mediates the coupled movement of potassium and chloride ions across the plasma membrane. This gene is expressed ubiquitously. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl- exit in NaCl absorbing epithelia.
仕様
Synonyms：Electroneutral potassium chloride cotransporter 1,Electroneutral potassium-chloride cotransporter 1,Erythroid K Cl cotransporter 1,Erythroid K-Cl cotransporter 1,FLJ40489,hKCC 1,hKCC1,KCC 1,KCC1,Potassium transport protein,Potassium/chloride cotransporter 1,S12A4,Slc12a4,Solute carrier family 12 （potassium/chloride transporters） member 4,Solute carrier family 12 member 4
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human SLC12A4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q9UP95
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
