Background:This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
仕様
Synonyms:NAD dependent deacetylase sirtuin 7,NAD dependent protein deacetylase sirtuin 7,NAD-dependent protein deacetylase sirtuin-7,Regulatory protein SIR2 homolog 7,Silent mating type information regulation 2 homolog,Silent mating type information regulation 2 S.cerevisiae homolog 7,SIR2 L7,SIR2 like protein 7,Sir2 related protein type 7,SIR2,S.CEREVISIAE,HOMOLOG-LIKE 7,SIR2-like protein 7,SIR2L 7,SIR2L7,SIR7,SIRT 7,SIRT7,Sirtuin 7,Sirtuin type 7,Sirtuin7
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human SIRT7
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000
Swissprot:Q9NRC8
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism