Background:The protein encoded by this gene is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
仕様
Synonyms:Cell proliferation-inducing gene 35 protein,EPC 1,EPC-1,EPC1,OI12,OI6,PEDF,PEDF,PIG 35,PIG35,Pigment epithelium derived factor,Pigment epithelium-derived factor,Proliferation inducing protein 35,serine (or cysteine) proteinase inhibitor,clade F (alpha-2 antiplasmin,pigment epithelium derived factor),member 1,Serpin F1,Serpin family F member 1,Serpin peptidase inhibitor clade F member 1,serpin peptidase inhibitor,clade F (alpha-2 antiplasmin,pigment epithelium derived factor),member 1,SERPINF 1,Serpinf1
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.2mg/mL
Immunogen:Recombinant protein of human SERPINF1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:P36955
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Neuroscience