Background:The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
仕様
Synonyms:CAP1,DJ-1,DJ1,DJ1 protein,Epididymis secretory sperm binding protein Li 67p,FLJ27376,FLJ34360,FLJ92274,HEL S 67p,Oncogene DJ1,OTTHUMP00000001348,OTTHUMP00000001349,OTTHUMP00000001350,OTTHUMP00000001351,PARK7,PARK7,Parkinson disease (autosomal recessive,early onset) 7,Parkinson disease protein 7,Parkinson protein 7,Protein DJ-1,SP22
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.1mg/mL
Immunogen:Recombinant protein of human PARK7
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:Q99497
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience, Signal transduction