Background：The p21 activated kinases （PAK） are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
仕様
Synonyms：C-t-PAK2,CB422,EC 2.7.11.1,Gamma PAK,Gamma-PAK,hPAK65,Kinase,p21 （CDKN1A） activated kinase 2,p21 （CDKN1A）-activated kinase 2a,p21 activated kinase 2,p21 protein （Cdc42/Rac）-activated kinase 2,p21 protein Cdc42 Rac activated kinase 2,p21-activated kinase 2,p21-activated kinase,65-KD,p21-activated protein kinase I,p21CDKN1A activated kinase 2,p27,p34,p58,p65PAK,PAK 2,PAK-2,PAK-2p34,Pak2,PAK2,PAK65,PAKgamma,S6 H4 kinase,S6/H4 kinase,Serine threonine protein kinase PAK 2,Serine/threonine protein kinase PAK 2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Recombinant protein of human PAK2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：50-1：200
Swissprot：Q13177
Isotype：IgG
Research Areas：Cancer, Cell Biology, Microbiology, Signal transduction
