Background:This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:Neuritin 1,Neuritin,NRN,Nrn1,NRN1,OTTHUMP00000015989,RP3 380B8.2 protein
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.7mg/mL
Immunogen:Recombinant protein of human NRN1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3