Background：This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：A/G specific adenine DNA glycosylase,A/G-specific adenine DNA glycosylase,Adenine DNA glycosylase,CYP2C,hMYH,MGC4416,MutY （E. coli） homolog,MutY homolog （E. coli）,MutY homolog,MutY,E. coli,homolog of,Mutyh,MUTYH,MYH,rMYH
Host：Rabbit
Reactivity：Human
Applications：WB,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human MUTYH
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：1000-1：5000
Swissprot：Q9UIF7
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
