Background：Ig （immunoglobulin） superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF10 （immunoglobulin superfamily, member 10）, also known as Calvaria mechanical force protein 608 （CMF608）, is a 2,623 amino acid secreted protein that contains an N-terminal signal peptide, six leucine-rich repeats （LRRs）, and 12 immunoglobulin-like repeats. IGSF10 exists as multiple alternatively spliced isoforms, and is expressed in bone. Specifically, expression of IGSF10 is limited to mesenchymal osteochondroprogenitors with fibroblast-like morphology, where it is thought to be involved in the maintenance of the osteochondroprogenitor cells pool and its down-regulation precedes terminal differentiation.
仕様
Synonyms：6530405F15Rik,9030224D03,AA409708,AA536958,Adlican2,AI414626,Calvaria mechanical force protein 608,CMF608,IGS10,IgSF10,Immunoglobulin superfamily member 10
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.7mg/mL
Immunogen：Recombinant protein of human IGSF10
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q6WRI0
Isotype：IgG
Research Areas：Cancer, Cell Biology, Developmental biology, Immunology, Signal transduction
