Background：This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
仕様
Synonyms：CFHL,CFHL1,CFHL1P,CFHR1,CFHR1P,Complement factor H related 1,Complement factor H related 1 pseudogene,Complement factor H related protein 1 precursor,Complement factor H-related protein 1,FHR 1,FHR-1,FHR1,FHR1,H factor （complement） like 1,H factor （complement） like 2,H factor like protein 1,H factor-like protein 1,H-factor-like 1,H36 1,H36 2,H36,HFL1,HFL2,MGC104329
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.2mg/mL
Immunogen：Recombinant protein of human CFHR1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
