Background:The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
仕様
Synonyms:Bmk,Hck 1,Hck,HCK,Hemopoietic cell kinase,JTK9,p59-HCK/p60-HCK,p59Hck,p59HCK/p60HCK,p61Hck,Tyrosine protein kinase HCK,Tyrosine-protein kinase HCK
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.2mg/mL
Immunogen:Recombinant protein of human HCK
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:P08631
Isotype:IgG
Research Areas:Cancer, Immunology, Signal transduction