Background:The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.
仕様
Synonyms:FABP 2,FABP2,FABPI,FABPI,Fatty acid binding protein 2 intestinal,Fatty acid binding protein,Fatty acid binding protein intestinal,Fatty acid-binding protein 2,Fatty acid-binding protein,I FABP,I-FABP,IFABP,intestinal,Intestinal fatty acid binding protein 2,Intestinal-type fatty acid-binding protein,MGC133132,OTTHUMP00000163925
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.6mg/mL
Immunogen:Recombinant protein of human FABP2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000, IHC 1:25-1:100
Swissprot:P12104
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Developmental biology, Signal transduction, Stem cells