Background：Endothelin-converting enzymes, such as ECE2 （EC 3.4.24.71）, are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family. It converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.
仕様
Synonyms：ECE 2,ECE-2,ECE2,ECE2,Endothelin converting enzyme 2,Endothelin-converting enzyme 2 region,Hypothetical protein MGC2408,KIAA0604,MGC17664,MGC78487
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.1mg/mL
Immunogen：Recombinant protein of human ECE2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：O60344
Isotype：IgG
Research Areas：Cardiovascular, Neuroscience, Signal transduction
