Background:This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
仕様
Synonyms:Dickkopf 3,Dickkopf 3 homolog (Xenopus laevis),Dickkopf 3 homolog,Dickkopf homolog 3,Dickkopf related protein 3,Dickkopf related protein 3 Precursor,Dickkopf WNT signaling pathway inhibitor 3,Dickkopf,Xenopus,homolog of,3,Dickkopf-3,Dickkopf-related protein 3,Dickkopf3,DKK 3,Dkk-3,DKK3,DKK3,hDkk 3,hDkk-3,hDkk3,Regulated in glioma,REIC,RIG,RIG-like 5-6,RIG-like 7-1
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:0.8mg/mL
Immunogen:Recombinant protein of human DKK3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000, IHC 1:50-1:200
Swissprot:Q9UBP4
Isotype:IgG
Research Areas:Cancer, Signal transduction, Stem cells