Background：DTX3 functions as an E3 ubiquitin ligase. Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context By similarity. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
仕様
Synonyms：Deltex3,Dtx3,DTX3,Protein deltex 3,Protein deltex-3,RING finger protein 154,RNF154
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human DTX3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：Q8N9I9
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Stem cells
