Background：This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
仕様
Synonyms：Aryl hydrocarbon hydroxylase,CP1B,CP1B1,Cyp1b1,CYPIB1,Cytochrome P450 1B1,Cytochrome P450 family 1 subfamily B polypeptide 1,Cytochrome P450 subfamily I （dioxin inducible） polypeptide 1 （glaucoma 3 primary infantile）,Flavoprotein linked monooxygenase,GLC3A,Microsomal monooxygenase,P4501B1,Xenobiotic monooxygenase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.2mg/mL
Immunogen：Recombinant protein of human CYP1B1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：Q16678
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
