Background：The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仕様
Synonyms：C16orf2,C16orf4,COX4 neighbor,COX4,neighbor of,COX4AL,Cox4nb,CX4NB,ER membrane protein complex subunit 8,FAM158B,family with sequence similarity 158,member B,Neighbor of COX4,NOC4,Protein FAM158B
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.8mg/mL
Immunogen：Recombinant protein of human EMC8
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
