Background：This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
仕様
Synonyms：Cbx 2,CBX2,CBX2,CDC A6,CDCA6,Cell division cycle associated 6,Cell division cycle associated6,chromobox homolog 2 （Pc class homolog,Drosophila）,Chromobox homolog 2,Chromobox homolog2,Chromobox protein homolog 2,hromobox homolog 2,M33,M33 polycomb like,MOD 2,MOD2,Modifier 3,Modifier3,Pc class homolog,Polycomb,SRXY5
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human CBX2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：Q14781
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
