Background:Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.
仕様
Synonyms:30K,Calcium activated neutral proteinase,Calcium activated neutral proteinase small subunit,Calcium dependent protease small subunit 1,Calcium dependent protease small subunit,Calcium-activated neutral proteinase small subunit,Calcium-dependent protease small subunit 1,Calcium-dependent protease small subunit,Calpain 4,Calpain 4 small subunit (30K),Calpain 4 small subunit,Calpain regulatory subunit,Calpain small polypeptide,Calpain small subunit 1,Calpain4,CalpainS1,CANP,CANP small subunit,CANPS,CAPN 4,CAPN S1,CAPN4,CAPNS 1,CAPNS,Capns1,CDPS,CPNS1,CSS 1,CSS1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human CAPNS1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:50-1:200
Swissprot:P04632
Isotype:IgG
Research Areas:Cancer, Cell Biology, Metabolism, Signal transduction