Background:The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:Calcium activated neutral proteinase 2,Calcium activated neutral proteinase,Calcium-activated neutral protease 2,catalytic subunit,Calcium-activated neutral proteinase 2,CALP80,Calpain 2 (m/II) large subunit,Calpain 2 catalytic subunit,Calpain 2 large catalytic subunit,Calpain 2 large subunit,Calpain 2,large [catalytic] subunit,Calpain large polypeptide L2,Calpain M type,Calpain M-type,Calpain-2 catalytic subunit,Calpain-2 large subunit,Calpain2,CAN2,CANP 2,CANP L2,CANP2,CANPL 2,CANPL2,CANPml,Capa2,CAPN 2,CAPN2,FLJ39928,M calpain,M calpin,M type,M-calpain,mCANP,Millimolar calpain,Millimolar-calpain
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.4mg/mL
Immunogen:Recombinant protein of human CAPN2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:P17655
Isotype:IgG
Research Areas:Cancer, Cell Biology, Metabolism, Signal transduction