Background:Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.
仕様
Synonyms:Activated protein C binding protein,Activated protein C-binding protein,Anticardiolipin cofactor,APC inhibitor,Apo-H,APOH,APOH,apolipoprotein H (beta-2-glycoprotein I),Apolipoprotein H,B2G1,B2GP1,B2GPI,Beta 2 glycoprotein I,Beta 2 glycoprotein I precursor,Beta(2)GPI,Beta-2-glycoprotein 1,Beta-2-glycoprotein I,BG,Glycoprotein 1,beta-2,Glycoprotein I,beta-2,OTTMUSP00000003033
Host:Rabbit
Reactivity:Human
Applications:WB,IHC,ELISA
Concentration:0.2mg/mL
Immunogen:Recombinant protein of human APOH
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:25-1:100
Swissprot:P02749
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Signal transduction