Background：The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette （ABC） transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies （ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White）. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.
仕様
Synonyms： ATP binding cassette sub family B member 8,ABCB8,ABCB8,ATP binding cassette sub family B （MDR/TAP） member 8,ATP binding cassette sub family B member 8 mitochondrial,ATP-binding cassette sub-family B member 8,EST328128,M ABC1,M-ABC1,MABC1,Mitochondrial ABC protein,mitochondrial,Mitochondrial ATP binding cassette 1,Mitochondrial ATP-binding cassette 1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.8mg/mL
Immunogen：Recombinant protein of human ABCB8
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：Q9NUT2
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
