Background:Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.
仕様
Synonyms:COX 6B,COX VIb 1,COX VIb-1,COX6B,COX6B1,COXG,COXVIb1,CX6B1,Cytochrome c oxidase subunit 6B1,Cytochrome c oxidase subunit VIb,Cytochrome c oxidase subunit VIb isoform 1,cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous),Cytochrome c oxidase subunit Vib polypeptide 1
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:0.7mg/mL
Immunogen:Recombinant protein of human COX6B1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:1000-1:5000, IHC 1:50-1:200
Swissprot:P14854
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction, Tags & Cell Markers