Background：The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X（L）, which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 （Th2） cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：12S1644,D12S1644,IL 4 STAT,IL-4 Stat,IL4 STAT,Interleukin 4 Induced,Interleukin 4 Induced Transcription Factor IL4 STAT,Signal transducer and activator of transcription 6,Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced,Signal Transducer And Activator Of Transcription 6 Nirs Variant 1,Signal transducer and activator of transcription 6,interleukin 4 induced,STAT 6,STAT interleukin4 induced,STAT,interleukin4 induced,Stat6,STAT6,STAT6B,STAT6C,Transcription factor IL 4 STAT
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.5mg/mL
Immunogen：Recombinant protein of human STAT6
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：P42226
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
