Background：This gene encodes a protein which is a member of the cysteine-aspartic acid protease （caspase） family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
仕様
Synonyms：Apoptotic protease Mch-2,Apoptotic protease MCH2,CASP-6,CASP6,CASP6,Caspase 6,Caspase 6 apoptosis related cysteine protease,Caspase 6,apoptosis related cysteine peptidase,Caspase-6 subunit p11,Mch2,OTTHUMP00000162742,OTTHUMP00000162743
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human CASP6
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：50-1：500
Swissprot：P55212
Isotype：IgG
Research Areas：Cancer, Cell Biology, Metabolism, Neuroscience
