Background：This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
仕様
Synonyms：AMYLOID BETA A4 PRECURSOR-LIKE PROTEIN 1,AMYLOID PRECURSOR-LIKE PROTEIN,Amyloid-like protein 1 precursor,APLP 1,APLP,APLP-1,Aplp1,APLP1,C30
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human APLP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
