Background:Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains.
仕様
Synonyms:MCT 4,MCT3,MCT4,Monocarboxylate transporter 3,Monocarboxylate transporter 4,MOT4,SLC16A3,Solute carrier family 16 member 3
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.5mg/mL
Immunogen:Synthetic peptide of human SLC16A3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:30-1:150
Swissprot:O15427
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction